NFL picks: 49ers vs. Giants Week 10 score predictions originally appeared on nbcsportsbayarea.comFor the second straight week, the 49ers (2-7) will play under the prime time lights. Last week, they beat the Raiders on Thursday Night Football. This week

Questions surround whether or not the San Francisco 49ers' meeting with the New York Giants will go ahead as planned on Monday. As wildfires spread through California, practices and games have been cancelled due to poor air quality from the smoke. On Friday, the Los Angeles Rams cancelled practice to give players and staff plenty of time to make sure their families are safe given the rapidly changing conditions.

Smoke from the Camp Fire in Northern California has affected the 49ers' practices, but currently, there are no plans to move Monday night's game against the New York Giants from Levi's Stadium. 49ers coach Kyle Shanahan said the team had to omit a few things from practice Friday as a result of the dwindling air quality. "Yes, it affected us because when we changed the practice time, we had to cut stuff out," Shanahan said.

Monday night's game between the New York Giants and San Francisco 49ers at Levi's Stadium could possibly be postponed or relocated due to smoke from the recent California wildfires. 49ers head coach Kyle Shanahan said Saturday that the game is still scheduled for Monday night but realizes that may change. "I know it's a possibility because of what's going on," Shanahan told reporters, per NBCSports.com.

1. Both the Giants and 49ers will be well-rested on Monday night, as New York was on a bye last week while San Francisco won 34-3 over Oakland on Thursday, giving the club 10 days off between games. While the extra rest could end up helping the 49ers, more time off has not led to increased success for the Giants in recent seasons.

After three weeks, the idea of the 49ers defense facing Saquon Barkley would have been considered a mismatch of considerable proportions. San Francisco was profoundly challenged, tackling-the-man-with-the-wise, and it didn't look as though they ever would be.

When the New York Giants' flashy wide receiver was asked Friday what he hoped his 1-7 team would do for the remainder of the season, Beckham didn't pull any punches. ''I think the goal is to win eight games, go 9-7 and go to the playoffs,'' Beckham said. ''It's not an easy task,'' Beckham added.

Nick Mullens remembers getting the phone call from Archie Manning inviting him to the prestigious Manning Passing Academy two summers ago. Mullens savored the chance to take part in the four-day clinic run by Archie and his two NFL quarterback sons, Eli and Peyton. Mullens especially relished the opportunity to watch Eli Manning take part in some of the drills.

Eli Manning does not feel any extra pressure when it comes to keeping his starting spot under center, but he does know the  New York Giants need to win. The Giants have had extra time to prepare for their Monday Night Football matchup against the San Francisco 49ers (2-7), where two struggling teams go head-to-head. New York have picked up only one win this season and improving that record is Manning's sole focus, despite speculation surrounding his future as the starting quarterback.

Evan Engram understands that he has all the tools to be a top tight end in the NFL. The New York Giants' second-year player, the team's first-round selection in 2017, has the size, speed and the drive to be a star. Engram has a propensity of dropping passes, especially in clutch situations.